Findings

Dosing

Kevin Lewis

August 27, 2013

Medical Marijuana Laws, Traffic Fatalities, and Alcohol Consumption

Mark Anderson, Benjamin Hansen & Daniel Rees
Journal of Law and Economics, May 2013, Pages 333-369

Abstract:
To date, 19 states have passed medical marijuana laws, yet very little is known about their effects. The current study examines the relationship between the legalization of medical marijuana and traffic fatalities, the leading cause of death among Americans ages 5-34. The first full year after coming into effect, legalization is associated with an 8-11 percent decrease in traffic fatalities. The impact of legalization on traffic fatalities involving alcohol is larger and estimated with more precision than its impact on traffic fatalities that do not involve alcohol. Legalization is also associated with sharp decreases in the price of marijuana and alcohol consumption, which suggests that marijuana and alcohol are substitutes. Because alternative mechanisms cannot be ruled out, the negative relationship between legalization and alcohol-related traffic fatalities does not necessarily imply that driving under the influence of marijuana is safer than driving under the influence of alcohol.

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Assessing the Effects of Medical Marijuana Laws on Marijuana and Alcohol Use: The Devil is in the Details

Rosalie Liccardo Pacula et al.
NBER Working Paper, August 2013

Abstract:
This paper sheds light on previous inconsistencies identified in the literature regarding the relationship between medical marijuana laws (MML) and recreational marijuana use by closely examining the importance of policy dimensions (registration requirements, home cultivation, dispensaries) and the timing of them. Using data from our own legal analysis of state MMLs, we evaluate which features are associated with adult and youth recreational use by linking these policy variables to data from the National Longitudinal Survey of Youth (NLSY97), the Youth Risk Behavior Survey (YRBS) and the Treatment Episodes Data System (TEDS). Our analyses control for state and year fixed effects, using within state policy changes over time to estimate the effect on changes in our outcome variables using a difference-in-differences approach. We find that while simple dichotomous indicators are generally not associated with marijuana use, specific dimensions of MMLs, namely home cultivation and legal dispensaries, are positively associated with marijuana use in each data set. Moreover, these same dimensions are tied to binge drinking and fatal alcohol automobile accidents as well. The findings have important implications for states considering legalization of marijuana, as regulating access to and promotion of dispensaries may be key for reducing the harms associated with these policies.

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Implicit Death Primes Increase Alcohol Consumption

Tsachi Ein-Dor et al.
Health Psychology, forthcoming

Objective: The authors examined whether priming thoughts of death are associated with increases in alcohol consumption.

Method: Research assistants handed out fliers that were stacked in a random order to pedestrians walking through campus (N = 377). These fliers served to remind them of either their death or of an aversive condition unrelated to death (severe back pain), which served as the control. Then they were solicited to purchase an alcoholic or nonalcoholic beverage.

Results: The authors used a 2 × 2 log-linear analysis, with type of prime (death-pain) and beverage type (alcoholic-nonalcoholic) as the independent variables and consumption (yes-no) as the outcome measure (11.9% of the total sample consumed a beverage). Results revealed that a greater percentage of students who received the death prime consumed alcohol (36.59%) versus students in the pain prime condition (8.94%), G2(4, N = 377) = 64.8, p < .001, W = .41. The type of prime (death-pain) did not influence the consumption of nonalcoholic beverages.

Conclusion: The current research indicates that death-related concerns may play a role in increasing the consumption of alcoholic beverages.

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Smoking, Muslim religious commitments, and the experience and behaviour of Ramadan in Pakistani men

Ziasma Haneef Khan, P.J. Watson & Zhuo Chen
Mental Health, Religion & Culture, August 2013, Pages 663-670

Abstract:
This study examined the possibility that smoking may interfere with Muslim commitments in general and with the experience and behaviour of Ramadan in particular. During Ramadan, a sample of 29 smoking and 46 non-smoking Pakistani men responded to measures of smoking, Religious Orientation, Religious Interest, Positive and Negative Ramadan Experience, and Ramadan Behaviour. Various indices of smoking predicted a disinterest in religion, less of an Intrinsic Religious Orientation, lower levels of Positive Ramadan Experience, higher Negative Ramadan Experience, and reductions in Ramadan Behaviour. These data offered preliminary support for the suggestion that smoking presents a challenge to Muslim beliefs and practices, especially during Ramadan.

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Interactive Effects of Discrimination and Racial Identity on Alcohol-Related Thoughts and Use

Laura Smart Richman et al.
Basic and Applied Social Psychology, July/August 2013, Pages 396-407

Abstract:
The interrelationships among racial discrimination, non race-based rejection, racial identity (RI), and alcohol cognitions and use were assessed in this research. In Study 1, individuals who experienced overt discrimination and who were high in RI were less likely than those low in RI to meet criteria for alcohol abuse disorder. In Study 2, discrimination and rejection were causally related to a faster reaction time in a lexical decision task to alcohol-related concepts as compared to neutral words, especially for those low in RI. Implications of discrimination and rejection on substance use and other risky health behaviors are discussed.

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Subjective Social Status and Substance Use Severity in a Young Adult Sample

Karen Finch et al.
Psychology of Addictive Behaviors, forthcoming

Abstract:
Subjective social status (SSS), an individual's subjective view of standing in society, has been shown to better predict health outcomes compared to objective measures of socioeconomic status (SES), including educational attainment and income. This study examines the relationship between SSS and severity of tobacco, alcohol, and marijuana use after controlling for objective measures of SES. Young adults (N = 1,987) aged 18-25 who reported smoking at least one cigarette in the past 30 days were recruited and surveyed anonymously online. Three separate structural equation models examined whether SSS was associated with severity of tobacco, alcohol, and marijuana use, controlling for personal and household income, years of education, employment status, and parental education. Household income (b = .31), employment status (b = .07), years of education (b = .09), and parental education (b = .16) were positively associated with SSS (all p values < .001); personal income was not significantly associated with SSS (p = .11). All three models adequately fit the data. SSS was negatively associated with severity of tobacco (b = -.13, p < .001) and marijuana use (b = -36, p = .02), but not alcohol use severity (b = .01, p = .56). Among young adults, higher subjective social status is associated with less severe tobacco and marijuana use, whereas alcohol use severity appears to be similar across socioeconomic class.

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Coffee, caffeine, and risk of completed suicide: Results from three prospective cohorts of American adults

Michel Lucas et al.
World Journal of Biological Psychiatry, forthcoming

Objective: To evaluate the association between coffee and caffeine consumption and suicide risk in three large-scale cohorts of US men and women.

Methods: We accessed data of 43,599 men enrolled in the Health Professionals Follow-up Study (HPFS, 1988-2008), 73,820 women in the Nurses' Health Study (NHS, 1992-2008), and 91,005 women in the NHS II (1993-2007). Consumption of caffeine, coffee, and decaffeinated coffee, was assessed every 4 years by validated food-frequency questionnaires. Deaths from suicide were determined by physician review of death certificates. Multivariate adjusted relative risks (RRs) were estimated with Cox proportional hazard models. Cohort specific RRs were pooled using random-effect models.

Results: We documented 277 deaths from suicide. Compared to those consuming ≤ 1 cup/week of caffeinated coffee (< 8 oz/237 ml), the pooled multivariate RR (95% confidence interval [CI]) of suicide was 0.55 (0.38-0.78) for those consuming 2-3 cups/day and 0.47 (0.27-0.81) for those consuming ≥ 4 cups/day (P trend < 0.001). The pooled multivariate RR (95% CI) for suicide was 0.75 (0.63-0.90) for each increment of 2 cups/day of caffeinated coffee and 0.77 (0.63-0.93) for each increment of 300 mg/day of caffeine.

Conclusions: These results from three large cohorts support an association between caffeine consumption and lower risk of suicide.

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Brief meditation training induces smoking reduction

Yi-Yuan Tang, Rongxiang Tang & Michael Posner
Proceedings of the National Academy of Sciences, 20 August 2013, Pages 13971-13975

Abstract:
More than 5 million deaths a year are attributable to tobacco smoking, but attempts to help people either quit or reduce their smoking often fail, perhaps in part because the intention to quit activates brain networks related to craving. We recruited participants interested in general stress reduction and randomly assigned them to meditation training or a relaxation training control. Among smokers, 2 wk of meditation training (5 h in total) produced a significant reduction in smoking of 60%; no reduction was found in the relaxation control. Resting-state brain scans showed increased activity for the meditation group in the anterior cingulate and prefrontal cortex, brain areas related to self-control. These results suggest that brief meditation training improves self-control capacity and reduces smoking.

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Peers and the Emergence of Alcohol Use: Influence and Selection Processes in Adolescent Friendship Networks

Wayne Osgood et al.
Journal of Research on Adolescence, September 2013, Pages 500-512

Abstract:
This study addresses not only influence and selection of friends as sources of similarity in alcohol use, but also peer processes leading drinkers to be chosen as friends more often than nondrinkers, which increases the number of adolescents subject to their influence. Analyses apply a stochastic actor-based model to friendship networks assessed five times from 6th through 9th grades for 50 grade cohort networks in Iowa and Pennsylvania, which include 13,214 individuals. Results show definite influence and selection for similarity in alcohol use, as well as reciprocal influences between drinking and frequently being chosen as a friend. These findings suggest that adolescents view alcohol use as an attractive, high-status activity and that friendships expose adolescents to opportunities for drinking.

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Increased Cigarette Tax is Associated with Reductions in Alcohol Consumption in a Longitudinal U.S. Sample

Kelly Young-Wolff et al.
Alcoholism, forthcoming

Background: Cigarette taxation has been recognized as one of the most significant policy instruments to reduce smoking. Smoking and drinking are highly comorbid behaviors, and the public health benefits of cigarette taxation may extend beyond smoking-related outcomes to impact alcohol consumption. The current study is the first to test whether increases in cigarette taxes are associated with reductions in alcohol consumption among smokers using a large, prospective U.S. sample.

Methods: Our sample included 21,473 alcohol consumers from the National Epidemiological Survey on Alcohol and Related Conditions (NESARC). Multiple linear regression analyses were conducted to evaluate whether increases in cigarette taxes between Waves 1 (2001 to 2002) and 2 (2004 to 2005) were associated with reductions in quantity and frequency of alcohol consumption, adjusting for demographics, baseline alcohol consumption, and alcohol price. Stratified analyses were conducted by sex, hazardous drinking status, and age and income group.

Results: Increases in cigarette taxes were associated with modest reductions in typical quantity of alcohol consumption and frequency of binge drinking among smokers. Cigarette taxation was not associated with changes in alcohol consumption among nonsmokers. In analyses stratified by sex, the inverse associations of cigarette taxes with typical quantity and binge drinking frequency were found only for male smokers. Further, the inverse association of cigarette taxation and alcohol consumption was stronger among hazardous drinkers (translating into approximately 1/2 a drink less alcohol consumption per episode), young adult smokers, and smokers in the lowest income category.

Conclusions: Findings from this longitudinal, epidemiological study suggest increases in cigarette taxes are associated with modest to moderate reductions in alcohol consumption among vulnerable groups. Additional research is needed to further quantify the public health benefits of cigarette taxation on alcohol consumption and to evaluate the potential broader crossover effects of cigarette taxation on other health behaviors.

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Are people overoptimistic about the effects of heavy drinking?

Frank Sloan et al.
Journal of Risk and Uncertainty, August 2013, Pages 93-127

Abstract:
We test whether heavy or binge drinkers are overly optimistic about probabilities of adverse consequences from these activities or are relatively accurate about these probabilities. Using data from a survey in eight cities, we evaluate the relationship between subjective beliefs and drinking. We assess accuracy of beliefs about several outcomes of heavy/binge drinking: reduced longevity, liver disease onset, link between alcohol consumption and Driving While Intoxicated (DWI), probability of an accident after drinking, accuracy of beliefs about encountering intoxicated drivers on the road, and legal consequences of DWI - ranging from being stopped to receiving fines and jail terms. Overall, there is no empirical support for the optimism bias hypothesis. We do find that persons consuming a lot of alcohol tend to be more overconfident about their driving abilities and ability to handle alcohol. However, such overconfidence does not translate into over-optimism about consequences of high levels of alcohol consumption.

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Psychedelics and Mental Health: A Population Study

Teri Krebs & Pål-Ørjan Johansen
PLoS ONE, August 2013

Background: The classical serotonergic psychedelics LSD, psilocybin, mescaline are not known to cause brain damage and are regarded as non-addictive. Clinical studies do not suggest that psychedelics cause long-term mental health problems. Psychedelics have been used in the Americas for thousands of years. Over 30 million people currently living in the US have used LSD, psilocybin, or mescaline.

Objective: To evaluate the association between the lifetime use of psychedelics and current mental health in the adult population.

Method: Data drawn from years 2001 to 2004 of the National Survey on Drug Use and Health consisted of 130,152 respondents, randomly selected to be representative of the adult population in the United States. Standardized screening measures for past year mental health included serious psychological distress (K6 scale), mental health treatment (inpatient, outpatient, medication, needed but did not receive), symptoms of eight psychiatric disorders (panic disorder, major depressive episode, mania, social phobia, general anxiety disorder, agoraphobia, posttraumatic stress disorder, and non-affective psychosis), and seven specific symptoms of non-affective psychosis. We calculated weighted odds ratios by multivariate logistic regression controlling for a range of sociodemographic variables, use of illicit drugs, risk taking behavior, and exposure to traumatic events.

Results: 21,967 respondents (13.4% weighted) reported lifetime psychedelic use. There were no significant associations between lifetime use of any psychedelics, lifetime use of specific psychedelics (LSD, psilocybin, mescaline, peyote), or past year use of LSD and increased rate of any of the mental health outcomes. Rather, in several cases psychedelic use was associated with lower rate of mental health problems.

Conclusion: We did not find use of psychedelics to be an independent risk factor for mental health problems.

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Selection and Influence Mechanisms Associated With Marijuana Initiation and Use in Adolescent Friendship Networks

Kayla de la Haye et al.
Journal of Research on Adolescence, September 2013, Pages 474-486

Abstract:
Friends are thought to influence adolescent drug use. However, few studies have examined the role of drugs in friendship selection, which is necessary to draw sound conclusions about influence. This study applied statistical models for social networks to test the contribution of selection and influence to associations in marijuana use among friends in two large high schools (N = 1,612; M age = 16.4). There was evidence for friend selection based on similar lifetime and current marijuana use at both schools, but friends were found to influence the initiation and frequency of adolescent marijuana use in just one of these schools. There was minimal evidence that peer effects were moderated by personal, school, or family risk factors.

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The Impact of Drug Treatment on Recidivism: Do Mandatory Programs Make a Difference? Evidence From Kansas's Senate Bill 123

Andres Rengifo & Don Stemen
Crime & Delinquency, September 2013, Pages 930-950

Abstract:
This study compares the recidivism of eligible drug possessors sentenced under Kansas's mandatory drug treatment policy (SB 123) to those of similar offenders receiving other sentences. Using multinomial logistic regression, the authors found that participation in SB 123 was generally associated with a decrease in the likelihood of recidivism. However, models relying on matched samples of offenders generated via propensity scores showed that SB 123 did not have a significant impact on recidivism rates relative to community corrections and actually increased recidivism rates relative to court services. The authors argue that the limited effect of SB 123 on recidivism stems from the net-widening effects often encountered with mandatory sentencing policies rather than inherent problems with the delivery of treatment.


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