Sanity
Social Inequalities in Suicide: The Role of Selective Serotonin Reuptake Inhibitors
Sean Clouston et al.
American Journal of Epidemiology, forthcoming
Abstract:
We aimed to examine the relationship between socioeconomic status (SES) and suicide associated with the introduction and diffusion of selective serotonin reuptake inhibitors (SSRIs). Negative binomial regression was used to estimate county-level suicide rates among persons aged 25 years or older using death certificate data collated by the National Center for Health Statistics from 1968 to 2009; SES was measured using the decennial US Census. The National Health and Nutrition Examination Survey and the Medical Expenditure Panel Survey were used to measure SSRI use. Once SSRIs became available in 1988, a 1% increase in SSRI usage was associated with a 0.5% lower suicide rate. Prior to the introduction of SSRIs, SES was not related to suicide. However, with each 1% increase in SSRI use, a 1–standard deviation (SD) higher SES was associated with a 0.6% lower suicide rate. In 2009, persons living in counties with SES 1 SD above the national average were 13.6% less likely to commit suicide than those living in counties with SES 1 SD below the national average — a difference of 1.9/100,000 adults aged ≥25 years. Higher SSRI use was associated with lower suicide rates among US residents aged ≥25 years; however, SES inequalities modified the association between SSRI use and suicide.
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A “Present” for the Future: The Unexpected Value of Rediscovery
Ting Zhang et al.
Psychological Science, forthcoming
Abstract:
Although documenting everyday activities may seem trivial, four studies reveal that creating records of the present generates unexpected benefits by allowing future rediscoveries. In Study 1, we used a time-capsule paradigm to show that individuals underestimate the extent to which rediscovering experiences from the past will be curiosity provoking and interesting in the future. In Studies 2 and 3, we found that people are particularly likely to underestimate the pleasure of rediscovering ordinary, mundane experiences, as opposed to extraordinary experiences. Finally, Study 4 demonstrates that underestimating the pleasure of rediscovery leads to time-inconsistent choices: Individuals forgo opportunities to document the present but then prefer rediscovering those moments in the future to engaging in an alternative fun activity. Underestimating the value of rediscovery is linked to people’s erroneous faith in their memory of everyday events. By documenting the present, people provide themselves with the opportunity to rediscover mundane moments that may otherwise have been forgotten.
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Waiting for Merlot: Anticipatory Consumption of Experiential and Material Purchases
Amit Kumar, Matthew Killingsworth & Thomas Gilovich
Psychological Science, forthcoming
Abstract:
Experiential purchases (money spent on doing) tend to provide more enduring happiness than material purchases (money spent on having). Although most research comparing these two types of purchases has focused on their downstream hedonic consequences, the present research investigated hedonic differences that occur before consumption. We argue that waiting for experiences tends to be more positive than waiting for possessions. Four studies demonstrate that people derive more happiness from the anticipation of experiential purchases and that waiting for an experience tends to be more pleasurable and exciting than waiting to receive a material good. We found these effects in studies using questionnaires involving a variety of actual planned purchases, in a large-scale experience-sampling study, and in an archival analysis of news stories about people waiting in line to make a purchase. Consumers derive value from anticipation, and that value tends to be greater for experiential than for material purchases.
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Youth Depression and Future Criminal Behavior
Mark Anderson, Resul Cesur & Erdal Tekin
Economic Inquiry, forthcoming
Abstract:
While the contemporaneous association between mental health problems and criminal behavior has been explored in the literature, the long-term consequences of such problems, depression in particular, have received much less attention. Using data from the National Longitudinal Study of Adolescent Health (Add Health), we examine the effect of depression during adolescence on the probability of engaging in a number of criminal behaviors later in life. In our analysis, we control for a rich set of individual-, family-, and neighborhood-level factors to account for conditions that may be correlated with both childhood depression and adult criminality. One novelty in our approach is the estimation of school and sibling fixed effects models to account for unobserved heterogeneity at the neighborhood and family levels. Furthermore, we exploit the longitudinal nature of our data set to account for baseline differences in criminal behavior. The empirical estimates show that adolescents who suffer from depression face a substantially increased probability of engaging in property crime. We find little evidence that adolescent depression predicts the likelihood of engaging in violent crime or the selling of illicit drugs. Our estimates imply that the lower-bound economic cost of property crime associated with adolescent depression is approximately 227 million dollars per year.
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Maya Tamir et al.
Emotion, forthcoming
Abstract:
According to expectancy-value models of self-regulation, people are motivated to act in ways they expect to be useful to them. For instance, people are motivated to run when they believe running is useful, even when they have nothing to run away from. Similarly, we propose an expectancy-value model of emotion regulation, according to which people are motivated to emote in ways they expect to be useful to them, regardless of immediate contextual demands. For instance, people may be motivated to get angry when they believe anger is useful, even when there is nothing to be angry about. In 5 studies, we demonstrate that leading people to expect an emotion to be useful increased their motivation to experience that emotion (Studies 1–5), led them to up-regulate the experience of that emotion (Studies 3–4), and led to emotion-consistent behavior (Study 4). Our hypotheses were supported when we manipulated the expected value of anxiety (Study 1) and anger (Studies 2–5), both consciously (Studies 1–4) and unconsciously (Study 5). We discuss the theoretical and pragmatic implications of the proposed model.
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Shuying Shen, Abdoul Sam & Eugene Jones
Journal of Consumer Affairs, forthcoming
Abstract:
While a number of studies have investigated the relationship between debt and psychological well-being, none so far has explored if and how this relationship evolves over time. We seek to fill this gap in the literature by empirically analyzing the impact of household credit card debt on debt stress. Using cross-sectional data collected by The Ohio State University's Consumer Finance Monthly survey between August 2008 and December 2010, we construct a debt stress index and categorize households into three groups based on the length of credit card indebtedness. Our empirical results provide statistical evidence of time-varying impacts of credit card debt on stress levels. Specifically, we find that debt stress for short-run debtors is more than twice that of long-run debtors. The results are robust across a range of econometric specifications.
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More than words: Contemplating death enhances positive emotional word use
Todd Kashdan et al.
Personality and Individual Differences, December 2014, Pages 171–175
Abstract:
Four experiments, three cross-sectional and one longitudinal, tested the hypothesis that contemplating one’s own death produces a shift toward the use of positive emotion words. Participants who wrote about their own death, compared with those who wrote about dental pain, uncertainty, and meaningless, used more positive emotions words in their narratives (Experiments 1a and 1b). Experiment 2 found that contemplating one’s own death enhanced positive emotional word use across different mortality salience manipulations and remained consistent over the course of a 6-day study. Experiment 3 showed that the more positive emotion words participants used when contemplating their mortality, the greater worldview defense they showed. These results suggest that word use offers insight into how the mind responds to the salience of mortality.
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Environmental enrichment as an effective treatment for autism: A randomized controlled trial
Cynthia Woo & Michael Leon
Behavioral Neuroscience, August 2013, Pages 487-497
Abstract:
Enriched sensorimotor environments enable rodents to compensate for a wide range of neurological challenges, including those induced in animal models of autism. Given the sensorimotor deficits in most children with autism, we attempted to translate that approach to their treatment. In a randomized controlled trial, 3–12 year-old children with autism were assigned to either a sensorimotor enrichment group, which received daily olfactory/tactile stimulation along with exercises that stimulated other paired sensory modalities, or to a control group. We administered tests of cognitive performance and autism severity to both groups at the initiation of the study and after 6 months. Severity of autism, as assessed with the Childhood Autism Rating Scale, improved significantly in the enriched group compared to controls. Indeed, 42% of the enriched group and only 7% of the control group had what we considered to be a clinically significant improvement of 5 points on that scale. Sensorimotor enrichment also produced a clear improvement in cognition, as determined by their Leiter-R Visualization and Reasoning scores. At 6 months, the change in average scores for the enriched group was 11.3 points higher than that for the control group. Finally, 69% of parents in the enriched group and 31% of parents in the control group reported improvement in their child over the 6-month study. Environmental enrichment therefore appears to be effective in ameliorating some of the symptoms of autism in children.
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Israel Liberzon et al.
JAMA Psychiatry, forthcoming
Objective: To examine the association of 3755 candidate gene single-nucleotide polymorphisms with PTSD development in interaction with a history of childhood trauma.
Design, Setting, and Participants: Genetic association study in an Ohio National Guard longitudinal cohort (n = 810) of predominantly male soldiers of European ancestry, with replication in an independent Grady Trauma Project (Atlanta, Georgia) cohort (n = 2083) of predominantly female African American civilians.
Results: Controlling for the level of lifetime adult trauma exposure, we identified the novel association of a single-nucleotide polymorphism within the promoter region of the ADRB2 (Online Mendelian Inheritance in Man 109690) gene with PTSD symptoms in interaction with childhood trauma (rs2400707, P = 1.02 × 10−5, significant after correction for multiple comparisons). The rs2400707 A allele was associated with relative resilience to childhood adversity. An rs2400707 × childhood trauma interaction predicting adult PTSD symptoms was replicated in the independent predominantly female African American cohort.
Conclusions and Relevance: Altered adrenergic and noradrenergic function has been long believed to have a key etiologic role in PTSD development; however, direct evidence of this link has been missing. The rs2400707 polymorphism has been linked to function of the adrenergic system, but, to our knowledge, this is the first study to date linking the ADRB2 gene to PTSD or any psychiatric disorders. These findings have important implications for PTSD etiology, chronic pain, and stress-related comorbidity, as well as for both primary prevention and treatment strategies.
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Dori Steinberg et al.
American Journal of Public Health, September 2014, Pages 1766-1773
Objectives: We evaluated the effect of a weight gain prevention intervention (Shape Program) on depression among socioeconomically disadvantaged overweight and obese Black women.
Methods: Between 2009 and 2012, we conducted a randomized trial comparing a 12-month electronic health–based weight gain prevention intervention to usual primary care at 5 central North Carolina community health centers. We assessed depression with the Patient Health Questionnaire (PHQ-8). We analyzed change in depression score from baseline to 12- and 18-month follow-up across groups with mixed models. We used generalized estimating equation models to analyze group differences in the proportion above the clinical threshold for depression (PHQ-8 score ≥ 10).
Results: At baseline, 20% of participants reported depression. Twelve-month change in depression scores was larger for intervention participants (mean difference = −1.85; 95% confidence interval = −3.08, −0.61; P = .004). There was a significant reduction in the proportion of intervention participants with depression at 12 months with no change in the usual-care group (11% vs 19%; P = .035). All effects persisted after we controlled for weight change and medication use. We saw similar findings at 18 months.
Conclusions: The Shape Program, which includes no mention of mood, improved depression among socioeconomically disadvantaged Black women.
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Tatyana Strekalova et al.
Behavioural Brain Research, forthcoming
Abstract:
Environmental factors can significantly affect disease prevalence, including neuropsychiatric disorders such as depression. The ratio of deuterium to protium in water shows substantial geographical variation, which could affect disease susceptibility. Thus the link between deuterium content of water and depression was investigated, both epidemiologically, and in a mouse model of chronic mild stress. We performed a correlation analysis between deuterium content of tap water and rates of depression in regions of the USA. Next, we used a 10-day chronic stress paradigm to test whether 2-week deuterium-depleted water treatment (91 ppm) affects depressive-like behavior and hippocampal structure. The effect of deuterium-depletion on sleep electrophysiology was also evaluated in naïve mice. There was a geographic correlation between a content of deuterium and the prevalence of depression across the USA. In the chronic stress model, depressive-like features were reduced in mice fed with deuterium-depleted water, and SERT expression was decreased in mice treated with deuterium-treated water compared with regular water. Five days of predator stress also suppressed proliferation in the dentate gyrus; this effect was attenuated in mice fed with deuterium-depleted water. Finally, in naïve mice, deuterium-depleted water treatment increased EEG indices of wakefulness, and decreased duration of REM sleep, phenomena that have been shown to result from the administration of selective serotonin reuptake inhibitors (SSRI). Our data suggest that the deuterium content of water may influence the incidence of affective disorder-related pathophysiology and major depression, which might be mediated by the serotoninergic mechanisms.
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Toxoplasma gondii and anxiety disorders in a community-based sample
Adam Markovitz et al.
Brain, Behavior, and Immunity, forthcoming
Abstract:
A growing body of literature suggests that exposure to the neurotropic parasite Toxoplasma gondii (T. gondii) is associated with increased risk of mental disorders, particularly schizophrenia. However, a potential association between T. gondii exposure and anxiety disorders has not been rigorously explored. Here, we examine the association of T. gondii infection with both anxiety and mood disorders. Participants (n = 484) were drawn from the Detroit Neighborhood Health Study, a population-representative sample of Detroit residents. Logistic regression was used to examine the associations between T. gondii exposure (defined by seropositivity and IgG antibody levels) and three mental disorders: generalized anxiety disorder (GAD), posttraumatic stress disorder (PTSD) and depression. We found that T. gondii seropositivity was associated with a 2 times greater odds of GAD (odds ratio (OR), 2.25; 95% confidence interval (CI), 1.11–4.53) after adjusting for age, gender, race, income, marital status, and medication. Individuals in the highest antibody level category had more than 3 times higher odds of GAD (OR, 3.35; 95% CI, 1.41–7.97). Neither T. gondii seropositivity nor IgG antibody levels was significantly associated with PTSD or depression. Our findings indicate that T. gondii infection is strongly and significantly associated with GAD. While prospective confirmation is needed, T. gondii infection may play a role in the development of GAD.
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Suicidal patients are deficient in vitamin D, associated with a pro-inflammatory status in the blood
Cécile Grudet et al.
Psychoneuroendocrinology, forthcoming
Background: Low levels of vitamin D may play a role in psychiatric disorders, as cross-sectional studies show an association between vitamin D deficiency and depression, schizophrenia and psychotic symptoms. The underlying mechanisms are not well understood, although vitamin D is known to influence the immune system to promote a T helper (Th)-2 phenotype. At the same time, increased inflammation might be of importance in the pathophysiology of depression and suicide. We therefore hypothesized that suicidal patients would be deficient in vitamin D, which could be responsible for the inflammatory changes observed in these patients.
Methods: We compared vitamin D levels in suicide attempters (n = 59), non-suicidal depressed patients (n = 17) and healthy controls (n = 14). Subjects were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, and went through a structured interview by a specialist in psychiatry. 25(OH)D2 and 25(OH)D3 were measured in plasma using liquid-chromatography mass-spectrometry (LC-MS). We further explored vitamin D's association with plasma IL-1β, IL-6 and TNF-α.
Results: Suicide attempters had significantly lower mean levels of vitamin D than depressed non-suicidal patients and healthy controls. 58 percent of the suicide attempters were vitamin D deficient according to clinical standard. Moreover, there was a significant negative association between vitamin D and pro-inflammatory cytokines in the psychiatric patients. Low vitamin D levels were associated with higher levels of the inflammatory cytokines IL-6 and IL-1β in the blood.
Conclusion: The suicide attempters in our study were deficient in vitamin D. Our data also suggest that vitamin D deficiency could be a contributing factor to the elevated pro-inflammatory cytokines previously reported in suicidal patients. We propose that routine clinical testing of vitamin D levels could be beneficial in patients with suicidal symptoms, with subsequent supplementation in patients found to be deficient.
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Economic Strain and Children's Behavior in the Aftermath of the Great Recession
Lindsey Jeanne Leininger & Ariel Kalil
Journal of Marriage and Family, October 2014, Pages 998–1010
Abstract:
Families across the income spectrum experienced subjective feelings of economic strain during the Great Recession. Existing evidence suggests that much of that economic strain did not arise from individual-specific economic shocks, such as unemployment or income loss, as much as it did from worry and uncertainty about the future. The authors tested a model in which a measure of subjective perceptions of economic strain was the key predictor of children's behavior problems and objective indicators of economic experiences were treated as control variables. To do so, they used new data from a population-based sample of children ages 4–17 (N = 303) living in southeast Michigan during the period 2009–2012. They found that economic strain exhibited a qualitatively large independent association with internalizing behavior problems for White — but not Black — children. This association was statistically significant over and above objective indicators of economic experiences and the family psychosocial context.
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Induction of a depression-like negativity bias by cathodal transcranial direct current stimulation
Larissa Wolkenstein et al.
Cortex, October 2014, Pages 103–112
Abstract:
Cognitive control (CC) over emotional distraction is of particular importance for adaptive human behaviour and is associated with activity in the left dorsolateral prefrontal cortex (dlPFC). Deficient CC, e.g. presenting as negativity bias, has been suggested to underlie many of the core symptoms of major depression (MD) and is associated with impairments of dlPFC function. Correspondingly, enhancement of dlPFC activity with anodal transcranial direct current stimulation (tDCS) can ameliorate these impairments in patients with MD. Here, we tested the hypothesis that a reduction of dlPFC activity by cathodal tDCS induces CC deficits, thus triggering a depression-like negativity bias in healthy subjects. Twenty-eight individuals participated in a double-blinded, balanced randomized crossover trial of cathodal (1mA, 20min) and sham tDCS applied to the left dlPFC. To assess CC we conducted a delayed response working memory (DWM) task and an arithmetic inhibition task (AIT) with pictures of varying valent content (negative, neutral, positive) during and immediately after stimulation. Cathodal tDCS led to impaired CC specifically over negative material as assessed by reduced response accuracy in the DWM and prolonged response latency in the AIT. Hence, the current study supports the notion that left dlPFC is critically involved in CC over negative material. Together with previously reported beneficial anodal effects, it indicates that the hypoactivation of left dlPFC causes deficits in CC over negative material, which is a possible aetiological mechanism of depression.
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Effects of Statewide Job Losses on Adolescent Suicide-Related Behaviors
Anna Gassman-Pines, Elizabeth Oltmans Ananat & Christina Gibson-Davis
American Journal of Public Health, October 2014, Pages 1964-1970
Objectives: We investigated the impact of statewide job loss on adolescent suicide-related behaviors.
Methods: We used 1997 to 2009 data from the Youth Risk Behavior Survey and the Bureau of Labor Statistics to estimate the effects of statewide job loss on adolescents’ suicidal ideation, suicide attempts, and suicide plans. Probit regression models controlled for demographic characteristics, state of residence, and year; samples were divided according to gender and race/ethnicity.
Results: Statewide job losses during the year preceding the survey increased girls’ probability of suicidal ideation and suicide plans and non-Hispanic Black adolescents’ probability of suicidal ideation, suicide plans, and suicide attempts. Job losses among 1% of a state’s working-age population increased the probability of girls and Blacks reporting suicide-related behaviors by 2 to 3 percentage points. Job losses did not affect the suicide-related behaviors of boys, non-Hispanic Whites, or Hispanics. The results were robust to the inclusion of other state economic characteristics.
Conclusions: As are adults, adolescents are affected by economic downturns. Our findings show that statewide job loss increases adolescent girls’ and non-Hispanic Blacks’ suicide-related behaviors.
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Craig Ewart et al.
Health Psychology, September 2014, Pages 977-985
Objectives: We tested the social action theory hypotheses that (a) psychological stress induced by struggling to control others (agonistic striving) is associated with higher levels of subjective somatic symptoms than stress induced by struggling to control the self (transcendence striving); (b) the association between agonistic striving and symptoms is moderated by the ability to tolerate pain; and (c) associations among agonistic goals, pain tolerance, and subjective symptoms are not explained by personality and affective traits or negative emotional responses to personal stressors.
Methods: Implicit motives and negative emotional reactivity to recurring personal stressors were assessed by Social Competence Interview in 333 adolescents and adults who participated in longitudinal research on functional abdominal pain at a university medical center. Pain tolerance was assessed by graduated thermal pain protocol; subjective somatic symptoms, and personality/affective traits assessed by questionnaires. The primary outcome measure was the self-reported severity of 35 somatic symptoms often experienced in the absence of diagnosable disease.
Results: All hypotheses were supported.
Conclusions: Nonconscious agonistic strivings may increase the perceived frequency and severity of subjective somatic symptoms; this tendency is greatly magnified by difficulty in self-regulating responses to painful stimuli. Implicit agonistic motives and their associations with symptoms are not explained by individual differences in trait neuroticism, anxiety, depression, anger, or low self-esteem or by negative emotional reactivity to a personal stressor. These findings may afford fruitful insights into mechanisms by which stressful social environments undermine health and suggest promising directions for clinical intervention.
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Alexa Tullett, Aaron Kay & Michael Inzlicht
Social Cognitive and Affective Neuroscience, forthcoming
Abstract:
Several prominent theories spanning clinical, social and developmental psychology suggest that people are motivated to see the world as a sensible orderly place. These theories presuppose that randomness is aversive because it is associated with unpredictability. If this is the case, thinking that the world is random should lead to increased anxiety and heightened monitoring of one’s actions and their consequences. Here, we conduct experimental tests of both of these ideas. Participants read one of three passages: (i) comprehensible order, (ii) incomprehensible order and (iii) randomness. In Study 1, we examined the effects of these passages on self-reported anxiety. In Study 2, we examined the effects of the same manipulation on the error-related negativity (ERN), an event-related brain potential associated with performance monitoring. We found that messages about randomness increased self-reported anxiety and ERN amplitude relative to comprehensible order, whereas incomprehensible order had intermediate effects. These results lend support to the theoretically important idea that randomness is unsettling because it implies that the world is unpredictable.
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Relations Between Narrative Coherence, Identity, and Psychological Well-being in Emerging Adulthood
Theodore Waters & Robyn Fivush
Journal of Personality, forthcoming
Objective: The hypothesis that the ability to construct a coherent account of personal experience is reflective, or predictive, of psychological adjustment cuts across numerous domains of psychological science. It has been argued that coherent accounts of identity are especially adaptive. We tested these hypotheses by examining relations between narrative coherence of personally significant autobiographical memories and three psychological well-being components (Purpose and Meaning; Positive Self View; Positive Relationships). We also examined the potential moderation of the relations between coherence and well-being by assessing the identity content of each narrative.
Method: We collected two autobiographical narratives of personally significant events from 103 undergraduate students and coded them for coherence and identity content. Two additional narratives about generic/recurring events were also collected and coded for coherence.
Results: We confirmed the prediction that constructing coherent autobiographical narratives is related to psychological well-being. Further, we found that this relation was moderated by the narratives’ relevance to identity and that this moderation held after controlling for narrative ability more generally (i.e. coherence of generic/recurring events).
Conclusion: These data lend strong support to the coherent narrative identity hypothesis and the prediction that unique events are a critical feature of identity construction in emerging adulthood.
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Emma Seppälä et al.
Journal of Traumatic Stress, August 2014, Pages 397–405
Abstract:
Given the limited success of conventional treatments for veterans with posttraumatic stress disorder (PTSD), investigations of alternative approaches are warranted. We examined the effects of a breathing-based meditation intervention, Sudarshan Kriya yoga, on PTSD outcome variables in U.S. male veterans of the Iraq or Afghanistan war. We randomly assigned 21 veterans to an active (n = 11) or waitlist control (n = 10) group. Laboratory measures of eye-blink startle and respiration rate were obtained before and after the intervention, as were self-report symptom measures; the latter were also obtained 1 month and 1 year later. The active group showed reductions in PTSD scores, d = 1.16, 95% CI [0.20, 2.04], anxiety symptoms, and respiration rate, but the control group did not. Reductions in startle correlated with reductions in hyperarousal symptoms immediately postintervention (r = .93, p < .001) and at 1-year follow-up (r = .77, p = .025). This longitudinal intervention study suggests there may be clinical utility for Sudarshan Kriya yoga for PTSD.
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Positive Effects of Basic Training on Cognitive Performance and Mood of Adult Females
Harris Lieberman et al.
Human Factors: The Journal of the Human Factors and Ergonomics Society, September 2014, Pages 1113-1123
Objective: This study investigated whether a stressful military training program, the 9- to 10-week U.S. Army basic combat training (BCT) course, alters the cognitive performance and mood of healthy young adult females.
Method: Two separate, within-subject studies were conducted with different BCT classes; in total 212 female volunteers were assessed before and after BCT. In Study 1, Four-Choice Reaction Time, Match-to-Sample, and Grammatical Reasoning tests were administered. The Psychomotor Vigilance Test (PVT) was administered in Study 2. The Profile of Mood States (POMS) was administered in both studies.
Results: In Study 1, reaction time to correct responses on all three of the performance tests improved from pre- to post-BCT. In Study 2, PVT reaction time significantly improved. All POMS subscales improved over time in the second study, whereas POMS subscales in the first study failed to meet criteria for statistically significant differences over time.
Conclusion: Cognition and mood substantially improved over military basic training. These changes may be a result of structured physical and mental training experienced during basic training or other factors not as yet identified.
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FKBP5 and CRHR1 polymorphisms moderate the stress–physical health association in a national sample
Jared Lessard & Alison Holman
Health Psychology, September 2014, Pages 1046-1056
Objective: Stressful life events experienced during childhood and as an adult negatively impact mental and physical health over the life span. This study examined polymorphisms from 2 hypothalamic–pituitary–adrenal axis-related genes previously associated with posttraumatic stress disorder — FKBP5 and CRHR1 — as moderators of the impact of child abuse and adult stress on physical health.
Method: A national, community-based subsample of non-Hispanic European American respondents (n = 527) from a prospective longitudinal 3-year study of stress and coping (N = 2,729) provided saliva for genotyping.
Results: FKBP5 (rs1360780) and CRHR1 (rs12944712) polymorphisms significantly interacted with child abuse and adult stress to predict increases in physical health ailments over 3 years. Child abuse and adult stress were strongly related to physician-diagnosed physical ailments among individuals with the risk alleles of both single nucleotide polymorphisms. Individuals carrying the low-risk homozygotic genotypes were protected from the long-term negative health implications of experiencing both child abuse and adult stress.
Conclusion: Consistent with theories linking the hypothalamic–pituitary–adrenal axis with stress-related disease, hypothalamic–pituitary–adrenal axis polymorphism genotypes moderated the association between exposure to child abuse/adult stress and long-term physical health outcomes in a national sample.
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You Are What You See and Choose: Agreeableness and Situation Selection
Konrad Bresin & Michael Robinson
Journal of Personality, forthcoming
Objective: Agreeableness positively predicts subjective well-being, but why does it do so? Recent theorizing has highlighted possible substrates related to emotion regulation. Following suit, the present studies focus on the situation selection stage of the emotion regulation sequence.
Methods: Undergraduate participants reported on their agreeableness levels and completed a picture viewing task (Studies 1 and 2) or a media choice task (Study 3).
Results: Studies 1 and 2 found that the tendency to view negative pictures for a longer period of time than positive pictures was evident at low levels of agreeableness and absent at high levels. The Study 3 paradigm asked individuals whether they typically choose to expose themselves to positive or negative stimuli across diverse media sources. Preferences for positive media were more pronounced at higher levels of agreeableness.
Conclusions: The results have systematic implications for understanding the emotional lives of disagreeable versus agreeable people.
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Weiting Ng & Ed Diener
Journal of Personality and Social Psychology, August 2014, Pages 326-338
Abstract:
This study explored the importance of financial satisfaction versus postmaterialist needs for subjective well-being (SWB). Using the Gallup World Poll, we examined whether financial satisfaction and postmaterialist needs (pertaining to autonomy, social support, and respect) were universal predictors of the different components of SWB across the world, and whether their effects were moderated by national affluence. Results showed that financial satisfaction was the strongest predictor of life evaluation, whereas respect was the strongest predictor of positive feelings. Both measures predicted negative feelings to some extent. Multilevel analyses also revealed moderating effects of societal wealth. The association between financial satisfaction and SWB and that between postmaterialist needs and SWB were stronger in richer nations compared with poorer ones. This suggests that developed economies should continue to focus on both material and psychological aspects, and not disregard economic gains, as both measures are essential to well-being.